, a non-psychoactive component of the cannabis plant, has generated significant interest among scientists and physicians in recent years—but how CBD exerts its therapeutic impact on a molecular level is still being sorted out by scientists. Cannabidiol is a pleiotropic drug in that it produces many effects through multiple molecular pathways.
Although CBD has a little binding affinity for either of the two cannabinoid receptors (CB1 and CB2), cannabidiol activates several non-cannabinoid receptors and ion channels. CBD also acts through various receptor-independent channels—for example, by delaying the “reuptake” of endogenous neurotransmitters (such as anandamide and adenosine) and by enhancing or inhibiting the binding action of certain G-coupled protein receptors.
Here are some of the ways that CBD confers its manifold therapeutic effects.